A scene is currently in place on Hopgarth Walk in Newton Heath.
This follows a report made to police earlier today (Tuesday 7 May 2019) of a concern for the welfare of a man.
A GMP spokesman said: “Officers attended and sadly discovered the bodies of two men who are believed to be in their 50s.
“Enquiries into the circumstances surrounding their deaths remain ongoing and a Home Office Post Mortem examination will take place over the coming days.
“The scene will remain in place while officers carry out their enquiries.”
Anyone with information should contact police 0161 856 1146 quoting reference number 1226 of 07/05/19 or the independent charity Crimestoppers, anonymously, on 0800 555 111.