The collision occurred at around 12.30am this morning (21 Aug).
A Cumbria Police spokesman said: “A silver VW Golf left the M6 between junctions 36 and 37 northbound near to Preston Patrick, went off the road and collided with a tree.
“It is not believed any other vehicles were involved in the incident.
“The driver and lone occupant of the car, a man aged 90 from Northern Ireland, suffered serious injuries.
“The man currently remains in hospital this morning with potentially life-changing injuries.”
Three fire engines attended the collision.
A Cumbria Fire and Rescue Service spokesman said: “Fighters extricated one casualty from the vehicle using hydraulic cutting equipment and spreading equipment, and the casualty was conveyed to hospital by ambulance.
“Crews were in attendance for approximately one hour.”
Officers would like to appeal for any witnesses to come forward. They would particularly like to hear from anyone with dash cam footage who was in the area at the time.
Contact police referencing incident 3 of 21 August 2019. Email: [email protected] Call non-emergency number: 101 Or Crimestoppers anonymously on 0800 555 111.